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KMID : 1123920120260030325
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Korean Journal of Oriental Physiology and Pathology
2012 Volume.26 No. 3 p.325 ~ p.329
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Antimicrobial Effect of Scutellariae Radix and Its Thermal Stability
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Kim Jong-Myoung
Lee Chul-Won
Ahn Yong-Tae
Lee Ho
Kim Choel
Kim Hyung-Woo
Cho Su-In
An Won-Gun
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Abstract
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The present study investigated the antimicrobial properties of medicinal herbs including Scutellariae Radix (SR: dried root of Scutellariae bicalensis Georgi). Among hot-water extracts of medicinal herbs tested in this study, SR extract showed the most potent antimicrobial activity with minimum inhibitory concentration (MIC) of 0.625 mg/mL. In particular, synergistic effects of antimicrobial activity were observed upon combined application of SR and chitooligosaccharide as indicated by MIC of 0.125 mg/mL and FIC (fractional inhibitory concentration) index of 0.45. Thermal stability analysis indicated that the components responsible for antimicrobial activity was stable for 8 months at 45℃. Antimicrobial activity was proven to be effective in foods as well as in cosmetics as comparable to that of the chemical preservatives.
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KEYWORD
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Scutellariae Radix, Herbal medicine, antibiotics, chitooliogssaccharide
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